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Jiawei Xing

Jiawei Xing

Graduate Student

The Ohio State University

I study protein structure and evolution using computational methods, including clustering algorithms, biological networks, phylogenetic analyses, molecular docking, etc. My current research topic focuses on the most common sensor, Per-Arnt-Sim (PAS) domains, in signal transduction systems. With a background in biology and an interest in computer science, I'm passionate about combining them together to better understand the secrets of life sciences.

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Latest

  • The PAS domain of the polarly localized histidine kinase FlrB in Vibrio cholerae controls class III flagellar transcription and contributes to intestinal colonization
  • Chemoreceptor family in plant-associated bacteria responds preferentially to the plant signal molecule glycerol 3-phosphate
  • Bacterial sensor evolved by decreasing complexity
  • The Campylobacter jejuni BumS sensor phosphatase detects the branched short-chain fatty acids isobutyrate and isovalerate as direct cues for signal transduction
  • Origin and functional diversification of PAS domain, a ubiquitous intracellular sensor
  • Transmembrane Transcription Regulators Are Widespread in Bacteria and Archaea
  • Photoactive Yellow Protein Represents a Distinct, Evolutionarily Novel Family of PAS Domains

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