Paroxysmal Kinesigenic Dyskinesia (PKD) is a rare neurological disorder characterized by
recurrent attacks of dyskinetic movements without alteration of consciousness that are often
triggered by the initiation of voluntary movements. Whole exome …
In contrast to Escherichia coli, a model organism for chemotaxis that has 5 chemoreceptors and a single chemosensory pathway, Pseudomonas aeruginosa PAO1 has a much more complex chemosensory network, which consists of 26 chemoreceptors feeding into …
Chemoreceptors in bacteria detect a variety of signals and feed this information into chemosensory pathways that represent a major mode of signal transduction. The five chemoreceptors from Escherichia coli have served as traditional models in the …
Bacterial two-component regulatory systems provide a simple stimulus-response coupling mechanism to enable bacteria to detect changes in environmental and intracellular conditions and respond accordingly by adjusting various cellular functions. Since …
Histidine kinases are key components of regulatory systems that enable bacteria to respond to environmental changes. Two major classes of histidine kinases are recognized on the basis of their modular design: classical (HKI) and chemotaxis specific …
“Sciences are not made but born….
“Bacteriology must henceforward be recognized as a broad and fundamental branch of science, coördinate with, rather than subordinate to, the other grand divisions of biology such as medicine, agriculture, zoölogy and …
In this issue of Structure, Lynch et al., 2017 reveal that the interaction between two key proteins in the bacterial flagellar motor results in a shared structural domain. This unusual arrangement keeps the corresponding genes together through the …
Gene duplication and loss are major driving forces in evolution. While many important genomic resources provide information on gene presence, there is a lack of tools giving equal importance to presence and absence information as well as web …
A rare chemotaxis receptor, Tlp11, has been previously identified in invasive strains of Campylobacter jejuni, the most prevalent cause of bacterial gastroenteritis worldwide. Here we use glycan and small-molecule arrays, as well as surface plasmon …